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Spatio-temporal characterization of phenotypic resistance in malaria vector species

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dc.contributor.author Eric, Ali Ibrahim
dc.contributor.author Mark, Wamalwa
dc.contributor.author John, Odindi
dc.contributor.author Tonnang, Henri E. Z.
dc.date.accessioned 2024-08-09T14:37:29Z
dc.date.available 2024-08-09T14:37:29Z
dc.date.issued 2024
dc.identifier.uri http://hdl.handle.net/20.500.12562/2022
dc.description PUBLICATION en_US
dc.description.abstract Malaria, a deadly disease caused by Plasmodium protozoa parasite and transmitted through bites of infected female Anopheles mosquitoes, remains a significant public health challenge in sub-Saharan Africa. Efforts to eliminate malaria have increasingly focused on vector control using insecticides. However, the emergence of insecticide resistance (IR) in malaria vectors pose a formidable obstacle, and the current IR mapping models remain static, relying on fixed coefficients. This study introduces a dynamic spatio-temporal approach to characterize phenotypic resistance in Anopheles gambiae complex and Anopheles arabiensis. We developed a cellular automata (CA) model and applied it to data collected from Ethiopia, Nigeria, Cameroon, Chad, and Burkina Faso. The data encompasses georeferenced records detailing IR levels in mosquito vector populations across various classes of insecticides. In characterizing the dynamic patterns of confirmed resistance, we identified key driving factors through correlation analysis, chi-square tests, and extensive literature review. en_US
dc.description.sponsorship Check PDF en_US
dc.publisher BMC Biology en_US
dc.rights Attribution-NonCommercial-ShareAlike 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/us/ *
dc.subject Spatio-temporal en_US
dc.subject phenotypic en_US
dc.subject malaria vector en_US
dc.title Spatio-temporal characterization of phenotypic resistance in malaria vector species en_US
dc.type Article en_US


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