Antimosquito and Antimicrobial Clerodanoids and a Chlorobenzenoid from Tessmannia species

Abstract

In our previous paper [1] we reported the isolation,structural determination, insect repellency and antimicrobial activity of nor-halimanoid diterpenes and some other compounds from Tessmannia densiflora.In continuation with investigations of Tanzania Tessmannia species for their antimosquito, antimicrobial and other constituents we now analyzed the root and stem barks of T. martiniana var pauloi Harms and T. martiniana var martiniana Harms. In Tanzania the plant species grow in the coastal evergreen forest reserves of Pugu and Zaraninge, respectively. None of them has previously been investigated chemically for bioactive or any other constituents. We now report the isolation and antimosquito, antibacterial and antifungal activities of ent-clerodane diterpenoids and a chlorobenzenoid from these plant species.