Journal Articles: Recent submissions

Now showing items 81-100 of 228

How do community health workers institutionalise: An analysis of Brazil’s CHW programme

Morgana, G. Martins Krieger; Clare, Wenham; Denise, Nacif Pimenta; Theresia, E. Nkya; Brunah, Schall; Ana Carolina, Nunes; Ana De, Menezes; Gabriela, Lotta (Taylor and Francis, 2021)

Community health workers (CHWs) are framed as the link betwee communities and the formal health system. CHWs must establish trusting relationships with the community and with the broader health service. How to find the ...
Molecular characterization of Plasmodium falciparum PHISTb proteins as potential targets of naturally-acquired immunity against malaria [version 2; peer review: 3 approved with reservations]

Tony, I. Isebe; Joel, L. Bargul; Bonface, M. Gichuki; James, M. Njunge; James, Tuju; Martin, K. Rono (Wellcome Open Research, 2021)

Background: Plasmodium falciparum causes the deadliest form of malaria in humans. Upon infection, the host’s infected red blood cells (iRBCs) are remodelled by exported parasite proteins in order to provide a niche for ...
Exploring the influence of different habitats and their volatile chemistry in modulating sand fly population structure in a leishmaniasis endemic foci, Kenya

Iman, B Hassaballa; Baldwyn, Torto; Catherine, L Sole; David, P Tchouassi (PLOS Neglected Tropical Disease, 2021)

Phlebotomine sand flies transmit many viral protozoan and bacterial pathogens of public health importance. Knowledge of the ecologic factors influencing their distribution at local scale can provide insights into disease ...
Afrotropical sand fly-host plant relationships in a leishmaniasis endemic area, Kenya

Iman, B Hassaballa; Catherine, L Sole; Xavier, Cheseto; Baldwyn, Torto; David, P Tchouassi (PLOS Neglected Tropical Disease, 2021)

The bioecology of phlebotomine sand flies is intimately linked to the utilization of environmental resources including plant feeding. However, plant feeding behavior of sand flies remains largely understudied for Afrotropical ...
Predicting the impact of outdoor vector control interventions on malaria transmission intensity from semi-field studies

Adrian, Denz; Margaret M, Njoroge; Mgeni M, Tambwe; Clara, Champagne; Fredros, Okumu; JoopJ.A, van Loon; Alexandra, Hiscox; Adam, Saddler; Ulrike, Fillinger; Sarah J, Moore; Nakul, Chitnis (BMC Parasite and Vector, 2021)

Background:Semi-field experiments with human landing catch (HLC) measure as the outcome are an important step in the development of novel vector control interventions against outdoor transmission of malaria since they ...
A surveyofmosquito-borneandinsect-specificvirusesinhospitalsandlivestockmarketsinwesternKenya

Tatenda, Chiuya; Daniel K, Masiga; Laura C, Falzon; ArmandaD.S, Bastos; Eric M, Fèvre; Jandouwe, Villinger (PLoS ONE, 2021)

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Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia

Abera, Deriba; Caleb K, Kibet; Teshome, Degefa; Lucas, Amenga‑Etego; Joel, L.Bargul; Lemu, Golassa (Malaria Journal, 2021)

Background:Plasmodium falciparum parasite populations in Ethiopia have been experiencing local selective pres‑sures from drugs and immunity, leading to evolutionary adaptation. However, there was a paucity of data on genomic ...
Insights into the Evolutionary Origin of Mediterranean Sandfly Fever Viruses

Marklewitz, M; Tchouassi, D.P; Hieke, C; Heyde, V; Torto, B; Sang, R; Junglen, S (mSphere, 2020)

Sandfly-transmitted phleboviruses (family Phenuiviridae, order Bunyavirales) are associated with febrile illness and infections of the nervous system in humans. These viruses are almost exclusively found in tropical areas ...
Citronellal perception and transmission by Anopheles gambiae s.s. (Diptera: Culicidae) females.

Wu, W; Li, S; Yang, M; Lin, Y; Zheng, K; Akutse, K. S (Scientific Reports, 2020)

Anopheles gambiae s.s. is a key vector of Plasmodium parasites. Repellents, which may be a promising alternative to pesticides used to control malaria mosquitoes. Although citronellal is a known mosquito repellent, its ...
Diversity and multiplicity of P. falciparum infections among asymptomatic school children in Mbita, western Kenya

Touray, A. O; Mobegi, V.A; Wamunyokoli, F; Herren, J.K (Scientific Reports, 2020)

Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important surrogate indicators for assessing malaria transmission intensity in different regions of endemicity. Determination of MOI and ...
High risk for human exposure to Rift Valley fever virus in communities living along livestock movement routes:

Tigoi, C; Sang, R; Chepkorir, E; Orindi, B; Arum, S.O; Mulwa, F; Mosomtai, G; Limbaso, S; Hassan, O.A; Irura, Z; Ahim, C; Evander, M (PLOS Neglected Tropical Diseases, 2020)

Introduction Multiple outbreaks of Rift Valley Fever (RVF) with devastating effects have occurred in East Africa. These outbreaks cause disease in both livestock and humans and affect poor households most severely. ...
Evolutionary genomics at the human-environment interface in Africa.

Svardal, H.; Rusuwa, B.; Linderoth, T.; Kiran, A.; Charmantier, A.; H. Michael, G. Lattorff; Cagan, A.; Ommeh, S. C.; Kamng’ona, A.; Katongo, C.; Santos, M.E; Durbin, R.; Kumwenda, B.; Visscher, P.M.; von der Heyden, S.; Participants of SMBE Malawi (Molecular Biology and Evolution, 2020)

We report on the first meeting of SMBE in Africa. SMBE Malawi was initiated to bring together African and international researchers who use genetics or genomics to study natural systems impacted by human activities. The ...
Evaluation of personal protection afforded by repellent-treated sandals against mosquito bites in south-eastern Tanzania

Sangoro, P.O; Gavana, T.; Finda, M.; Mponzi, W.; Hape, E.; Limwagu, A.; Govella, N.J.; Chaki, P.; Okumu, F.O (Malaria Journal, 2020)

Background Outdoor and early evening mosquito biting needs to be addressed if malaria elimination is to be achieved. While indoor-targeted interventions, such as insecticide-treated nets and indoor residual spraying, ...
Review: Exploiting insect-specific viruses as a novel strategy to control vector-borne disease.

Patterson, E.I.; Villinger, J.; Muthoni, J. N.; Dobel-Ober L and Hughes, G.L. (Current Opinion in Insect Science, 2020)

Novel insect-specific viruses (ISVs) are being discovered in many important vectors due to advances in sequencing technology and a growing awareness of the virome. Several in vitro and in vivo studies indicate that ISVs ...
How to turn collectors of edible insects into mini-livestock farmers: Multidimensional sustainability challenges to a thriving industry

Nischalke, S.; Wagler, I.; Tanga, C.; Allan, D.; Phankaew, C.; Ratompoarison, C.; Razafindrakotomamonjy, A.; Kusia, E. (Global Food Security, 2020)

Edible insects reared under suitable climatic conditions are an efficient and ecological food source. However, most of the insects come from wild collection and not from farms (FAO, 2013). To establish insects as part of ...
Evaluating effectiveness of screening house eaves as a potential intervention for reducing indoor vector densities and malaria prevalence in Nyabondo, western Kenya.

Ng’ang’a, P.N.; Okoyo, C.; Mbogo, C.; Mutero, C. M. (Malaria Journal, 2020)

Background Mosquito-proofing of houses using wire mesh screens is gaining greater recognition as a practical intervention for reducing exposure to malaria transmitting mosquitoes. Screening potentially protects all persons ...
Widespread army ant aversion among East African jumping spiders (Salticidae).

Nelson, X.J; Aguilar-Arguello, S.; Jackson, R.R (Journal of Ethology, 2020)

Jumping spiders (Salticidae) typically prey on a variety of arthropods of similar size to themselves, but rarely on ants. Using 28 salticid species from East Africa, we frst investigated vision-based aversion to ants by ...
Impact of Plasmodium falciparum small-sized extracellular vesicles on host peripheral blood mononuclear cells [version 1; peer review: awaiting peer review.

Mwangi, S.J; Gwela, A.; Kioko, M.; Bargul, J.L; Nduati, E. W.; Ndungu, F.M; Bejon, P.; Rayner, J.C.; Abdi, A.I. (Wellcome Open Research, 2020)

Background: Exagerated immune activation has a key role in the pathogenesis of malaria. During blood-stage infection, Plasmodium falciparum can interact directly with host immune cells through infected red blood cells ...
Evaluating the impact of larviciding with Bti and community education and mobilization as supplementary integrated vector management interventions for malaria control in Kenya and Ethiopia

Mutero, C. M.; Okoyo, C.; Girma, M.; Mwangangi, J.; Kibe, L.; Ng’ang’a, P.; Kussa, D.; Affognon, H.; Mbogo, C. M. (Malaria Journal, 2020)

Background Malaria prevention in Africa is mainly through the use of long-lasting insecticide treated nets (LLINs). The objective of the study was to assess the effect of supplementing LLINs with either larviciding with ...
Arboviruses and blood-meal sources in zoophilic mosquitoes at human-wildlife interfaces in Kenya.

Musa, A.A; Muturi, M.W.; Musyoki, A.M; Ouso, D.O.; Oundo, J.W; Makhulu, E.E; Wambua, L.; Villinger, J.; Jeneby, M.M (Vector-Borne and Zoonotic Diseases, 2020)

Background: Zoophilic mosquitoes play an important role in the transmission of arboviruses of medical importance at human-wildlife interfaces, yet arbovirus surveillance efforts have been focused mostly on anthropophilic ...

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