Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals

Clarence, M. Mang’era; Fathiya, M. Khamis; Erick, O. Awuoche; Ahmed, Hassanali; Fidelis Levi, Odhiambo Ombura; Paul, O. Mireji

dc.contributor.author	Clarence, M. Mang’era
dc.contributor.author	Fathiya, M. Khamis
dc.contributor.author	Erick, O. Awuoche
dc.contributor.author	Ahmed, Hassanali
dc.contributor.author	Fidelis Levi, Odhiambo Ombura
dc.contributor.author	Paul, O. Mireji
dc.date.accessioned	2021-09-02T08:47:17Z
dc.date.available	2021-09-02T08:47:17Z
dc.date.issued	2021
dc.identifier.uri	http://hdl.handle.net/123456789/1517
dc.description.abstract	Insect growth regulators (IGRs) can control insect vector populations by disrupting growth and development in juvenile stages of the vectors. We previously identified and described the curry tree (Murraya koenigii (L.) Spreng) phytochemical leaf extract composition (neplanocin A, 3-(1-naphthyl)-l-alanine, lumiflavine, terezine C, agelaspongin and murrayazolinol), which disrupted growth and development in Anopheles gambiae sensu stricto mosquito larvae by inducing morphogenetic abnormalities, reducing locomotion and delaying pupation in the mosquito. Here, we attempted to establish the transcriptional process in the larvae that underpins these phenotypes in the mosquito.	en_US
dc.description.sponsorship	Grand Challenges Canada	en_US
dc.publisher	BMC Parasite and Vector	en_US
dc.rights	Attribution-NonCommercial-ShareAlike 3.0 United States	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/3.0/us/	*
dc.subject	Anopheles gambiae s.s	en_US
dc.subject	Growth disruption	en_US
dc.subject	Mosquito larvae	en_US
dc.subject	Diferential gene expression	en_US
dc.subject	Murraya koenigii	en_US
dc.title	Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals	en_US
dc.type	Article	en_US